ea0099rc5.7 | Rapid Communications 5: Pituitary and Neuroendocrinology | Part I | ECE2024
Fellinger Paul
, Pfleger Lorenz
, Beiglboeck Hannes
, Baumgartner Clemens
, Marella Nara
, Micko Alexander
, Wolfsberger Stefan
, Vila Greisa
, Lmger Anton
, Kautzky-Willer Alexandra
, Krssak Martin
, Scherer Thomas
, Wolf Peter
, Krebs Michael
, Winhofer Yvonne
Overview: Despite marked insulin resistance, patients with active acromegaly have low hepatocellular lipid content (IHL) and an unfavourable hepatic lipid composition (UI). As previously shown, inadequate mitochondrial activity in the liver might counteract lipid accumulation in the liver. The purpose of this study was to understand changes in hepatic metabolism, and lipidomic profile with therapy of acromegaly.Methods: We prospectively included thirteen...